Virtual screening application ReverseScreen3D using VeraChem’s VConf for generation of 3D ligand conformations
Prof. Richard Jackson’s group at the University of Leeds has released a Web based virtual screening application ReverseScreen3D, which uses VeraChem’s VConf package for 3D ligand conformer generation: “Vconf (v2.0 from VeraChem), which uses a stochastic method for conformer searching, was chosen because it has been shown to be highly effective at reproducing bioactive conformations.” Kinnings, S. L. and R. M. Jackson (2011). “ReverseScreen3D: A Structure-Based Ligand Matching Method To identify Protein Targets. “Journal of Chemical Information and Modeling 51(3): 624-634. DOI: 10.1021/ci1003174
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